Aedes aegypti mosquitoes are responsible for dengue, chikungunya, and Zika virus transmission in tropical and subtropical areas around the world. Due to the absence of vaccines or antiviral drugs for human treatment, the majority of control strategies are targeted at Ae. aegypti ...
Autor(es): Vladimir Valentinovich Kouznetsov. Stelia Carolina Mendez. Jonny Edward Duque.
Alpha-Amino nitrile compounds have a profound impact on bio-chemical sciences, as they have been prepared from inexpensive starting materials and have become valuable intermediates in the chemical synthesis of vitally important heterocyclic and carbocyclic molecules, which serve...
Autor(es): Vladimir Valentinovich Kouznetsov.
The one-pot diastereoselective synthesis of new N-substituted octahydroacridines was successfully achieved via BiCl3-catalyzed intramolecular cationic imino Diels?Alder reaction in good yields employing N-protected anilines and (±)-citronellal as substrates under mild conditions....
Autor(es): Arnold Rafael Romero. Vladimir Valentinovich Kouznetsov. Edgar Mauricio de Jesús Acelas Mantilla.
Los grupos protectores alilo y bencilo fueron facilmente adicionados sobre una serie de ácidos (ciclo)alquil alpha-hidroxicarboxílicos mediante una modificación a la esterificación deSteglich, utilizando O-alil y O-bencil-N,N´-diciclohexilisoureas. Los alil y bencil ésteres fue...
Autor(es): Cesar Adolfo Sanchez. Elvis Robles. Juan Manuel Urbina.
The title compound, C17H20O3, the cycloheptane ring adopts a slightly distorted chair conformation. The planar five-membered ring is inclined at 57.13 (11) to the phenyl ring of the benzyloxy substituent. In the crystal structure, C?HO and C?H hydrogen bonds generate layers in th...
Autor(es): Juan Manuel Urbina. Jose Antonio Henao. Elvis Robles. Jose Hernando Quintana.
El estudio de los sistemas heterocíclicos constituye una de las áreas más versátiles e importantes de la química orgánica. Dentro de estos, los derivados de la furan-2[5H]-ona, conocidos comúnmente como ??,?-butenolidas, han adquirido un creciente interés en su estudio en las últ...
Autor(es): Juan Manuel Urbina. Andres Felipe Leon.